9-diazaspiro[5.5]undecane-2-carboxylate
2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester
CAS: 1023595-19-8
Molecular Formula: C14H26N2O2
9-diazaspiro[5.5]undecane-2-carboxylate - Names and Identifiers
9-diazaspiro[5.5]undecane-2-carboxylate - Physico-chemical Properties
| Molecular Formula | C14H26N2O2 |
| Molar Mass | 254.37 |
| Density | 1.05 |
| Boling Point | 354.1±35.0 °C(Predicted) |
| pKa | 11.22±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Irritant, Refrigerate |
| MDL | MFCD10700117 |
9-diazaspiro[5.5]undecane-2-carboxylate - Risk and Safety
| Hazard Symbols | F - Flammable |
| Risk Codes | 11 - Highly Flammable |
| Safety Description | S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. |
| TSCA | No |
9-diazaspiro[5.5]undecane-2-carboxylate - Introduction
2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester is an organic compound with a chemical formula of C14H27NO2. It is a solid, commonly used in the form of colorless to yellow crystals. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to yellow solid
-Molecular weight: 253.37g/mol
-Melting point: about 60-65°C
-Boiling point: about 350-400°C
-Solubility: Soluble in organic solvents, such as ethanol, dimethyl sulfoxide, etc.; basically insoluble in water.
Use:
2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester has certain application value in the field of medicinal chemistry and organic synthesis, and can be used as reagents and intermediates in organic synthesis reactions. It can be used to synthesize biologically active molecules, such as antitumor agents, antibiotics, etc.
Preparation Method:
2,9-Diazaspiro[5.5] The preparation method of undecane-9-carboxylic acid tert-butyl ester is relatively complicated, and it is usually obtained through several steps of organic synthesis reaction. A common synthetic route is by the esterification of diazaspiro [5.5] undecan-9-one with tert-butanoic acid.
Safety Information:
- 2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester is not currently classified as a particularly dangerous chemical. However, as basic guidelines for the safe use and handling of chemical substances, the following safety and protective measures still need to be followed:
-Wear appropriate protective gloves, glasses, and lab coats when using the compound.
-During operation, avoid inhalation, ingestion or skin contact to avoid dust and steam.
-Personal hygiene should be properly managed and contaminated clothing should be cleaned and replaced in a timely manner.
-The compound should be stored in a dry, ventilated and sealed container, avoiding contact with oxygen, heat sources or sparks.
IMPORTANT:
Since the synthesis and use of 2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester requires professional laboratory equipment and technical knowledge, it can only be operated and used by relevant professionals under suitable experimental conditions. Anyone should carefully understand the safety information of the substance and follow the operating procedures before using it.
Nature:
-Appearance: Colorless to yellow solid
-Molecular weight: 253.37g/mol
-Melting point: about 60-65°C
-Boiling point: about 350-400°C
-Solubility: Soluble in organic solvents, such as ethanol, dimethyl sulfoxide, etc.; basically insoluble in water.
Use:
2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester has certain application value in the field of medicinal chemistry and organic synthesis, and can be used as reagents and intermediates in organic synthesis reactions. It can be used to synthesize biologically active molecules, such as antitumor agents, antibiotics, etc.
Preparation Method:
2,9-Diazaspiro[5.5] The preparation method of undecane-9-carboxylic acid tert-butyl ester is relatively complicated, and it is usually obtained through several steps of organic synthesis reaction. A common synthetic route is by the esterification of diazaspiro [5.5] undecan-9-one with tert-butanoic acid.
Safety Information:
- 2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester is not currently classified as a particularly dangerous chemical. However, as basic guidelines for the safe use and handling of chemical substances, the following safety and protective measures still need to be followed:
-Wear appropriate protective gloves, glasses, and lab coats when using the compound.
-During operation, avoid inhalation, ingestion or skin contact to avoid dust and steam.
-Personal hygiene should be properly managed and contaminated clothing should be cleaned and replaced in a timely manner.
-The compound should be stored in a dry, ventilated and sealed container, avoiding contact with oxygen, heat sources or sparks.
IMPORTANT:
Since the synthesis and use of 2,9-Diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester requires professional laboratory equipment and technical knowledge, it can only be operated and used by relevant professionals under suitable experimental conditions. Anyone should carefully understand the safety information of the substance and follow the operating procedures before using it.
Last Update：2024-04-09 21:04:16
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